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<meta name="keywords" content="150, Kronik, HCV, Prognoz, enfeksiyonunun, ABD’de, her, yıl, 8-13, bin, ölümden, sorumlu, olduğu,, HIV, enfeksiyonundan, daha, fazla, ölüme, neden, olduğu, gösterilmiştir., KHC, ve, kompanse, sirozda, yaşam, beklentisi, iyi, olmakla, birlikte,, dekompanse, siroz, HCC, gelişen, hastalarda, beklenen, süresi, belirgin, şekilde, kısalmak-, tadır., Kompanse, hastalarında, karaciğer, transplantasyonu, yapılmaksızın, 5, yıllık, sağkalım, yaklaşık, %80, iken,, sirozlularda, %50, civarın-, dadır., Ölüm, veya, sonlanım, noktası, olarak, kabul, edildiğinde,, sirozlu, hastaların, yılda, %4.5’i,, %6.3’ü, bu, noktasına, ulaşmaktadır., Trombositopeni,, hipoalbüminemi,, özofagus, varis, varlığı, yaş, ile, bağım-, sız, ilişkili, bulunmuştur., Kaynaklar, 1., Chopra, S,, Clinical, manifestations, and, natural, history, of, chronic, hepatitis, C, virus, infection., Uptodate,, last, updated:, Apr, 30,, 2015., 2., Terrault, N.A,, S., Diagnosis, evaluation, infection, Mar, 19,, 3., EASL, Recommendations, on, Treatment, Hepatitis, J, Hepatol., 2015, Jul;63(1):199-236., doi:, 10.1016/j.jhep.2015.03.025., Epub, 21., 4., Wedemeyer, H., C., Eds;, Feldman, M,, Friedman, LS,, Brandt, LJ,, Sleisenger, Fordtran's, Gastrointestinal, Liver, Disease-, 2, Volume, Set,, 10th, Edition., 1332-1339., 5., Yılmaz, G., hepatitlerde, invaziv, olmayan, testlerin, karşılaştırılması., Eds, Tabak, F,, Tosun, Viral, Hepatit, 2013., İstanbul,, 199-214." />
<title>Hepatit B'den D'ye Hep Güncel</title>
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<h1>Hepatit B'den D'ye Hep Güncel - page 162</h1>
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<span class="font1 fontPosition" style="opacity:1;">150</span>
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<strong>Kronik HCV</strong>
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<strong>Prognoz</strong>
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<span class="font2 fontPosition" style="opacity:1;">HCV enfeksiyonunun ABD’de her yıl 8-13 bin ölümden sorumlu olduğu, HIV</span>
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<span class="font2 fontPosition" style="opacity:1;">enfeksiyonundan daha fazla ölüme neden olduğu gösterilmiştir. KHC ve</span>
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<span class="font2 fontPosition" style="opacity:1;">kompanse sirozda yaşam beklentisi iyi olmakla birlikte, dekompanse siroz</span>
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<span class="font2 fontPosition" style="opacity:1;">ve HCC gelişen hastalarda beklenen yaşam süresi belirgin şekilde kısalmak-</span>
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<span class="font2 fontPosition" style="opacity:1;">tadır. Kompanse siroz hastalarında karaciğer transplantasyonu yapılmaksızın</span>
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<span class="font2 fontPosition" style="opacity:1;">5 yıllık sağkalım yaklaşık %80 iken, dekompanse sirozlularda %50 civarın-</span>
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<span class="font2 fontPosition" style="opacity:1;">dadır. Ölüm veya karaciğer transplantasyonu sonlanım noktası olarak kabul</span>
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<span class="font2 fontPosition" style="opacity:1;">edildiğinde, kompanse sirozlu hastaların yılda %4.5’i, dekompanse sirozlu</span>
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<span class="font2 fontPosition" style="opacity:1;">hastaların yılda %6.3’ü bu sonlanım noktasına ulaşmaktadır. Trombositopeni,</span>
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<span class="font2 fontPosition" style="opacity:1;">hipoalbüminemi, özofagus varis varlığı ve yaş bu sonlanım noktası ile bağım-</span>
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<span class="font2 fontPosition" style="opacity:1;">sız olarak ilişkili bulunmuştur.</span>
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<strong>Kaynaklar</strong>
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<span class="font4 fontPosition" style="opacity:1;">1.</span>
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<span class="font4 fontPosition" style="opacity:1;">Chopra S, Clinical manifestations and natural history of chronic hepatitis C virus</span>
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<span class="font4 fontPosition" style="opacity:1;">infection. Uptodate, last updated: Apr 30, 2015.</span>
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<span class="font4 fontPosition" style="opacity:1;">2.</span>
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<span class="font4 fontPosition" style="opacity:1;">Terrault N.A, Chopra S. Diagnosis and evaluation of chronic hepatitis C virus</span>
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<span class="font4 fontPosition" style="opacity:1;">infection Uptodate, last updated: Mar 19, 2015.</span>
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<span class="font4 fontPosition" style="opacity:1;">3.</span>
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<span class="font4 fontPosition" style="opacity:1;">EASL Recommendations on Treatment of Hepatitis C 2015. J Hepatol. 2015</span>
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<span class="font4 fontPosition" style="opacity:1;">Jul;63(1):199-236. doi: 10.1016/j.jhep.2015.03.025. Epub 2015 Apr 21.</span>
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<span class="font4 fontPosition" style="opacity:1;">4.</span>
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<span class="font4 fontPosition" style="opacity:1;">Wedemeyer H. Hepatitis C. Eds; Feldman M, Friedman LS, Brandt LJ, Sleisenger and</span>
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<span class="font4 fontPosition" style="opacity:1;">Fordtran's Gastrointestinal and Liver Disease- 2 Volume Set, 10th Edition. 1332-1339.</span>
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<span class="font4 fontPosition" style="opacity:1;">5.</span>
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<span class="font4 fontPosition" style="opacity:1;">Yılmaz G. Kronik hepatitlerde invaziv ve invaziv olmayan testlerin karşılaştırılması.</span>
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<span class="font4 fontPosition" style="opacity:1;">Eds Tabak F, Tosun S. Viral Hepatit 2013. İstanbul, 199-214.</span>
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