<!DOCTYPE html SYSTEM "about:legacy-compat"> <html xmlns="http://www.w3.org/1999/xhtml"> <head> <meta http-equiv="Content-Type" content="text/html; charset=windows-1254" /> <meta name="description" content="Hepatit B'den D'ye Hep Güncel" /> <meta name="keywords" content="15, Gastroenterol, 2007;13:14-21., 3., Glebe, D,, Urban, S., Viral, and, cellular, determinants, involved, in, hepadnaviral, entry., World, J, 2007;13:22-38., 4., Ganem, Prince, AM., Hepatitis, B, infection:, natural, history, clinical, consequences., New, England, Journal, of, Medicine, 2004;350:1118-1129., 5., Beck, J,, Nassal, M., virus, replication., 2007;13(1):48-, 64., 6., Wang, GH,, Seeger, C., Novel, mechanism, for, reverse, transcription, hepatitis, viruses., Virol, 1993;67:6507-6512., 7., Block, TM,, Guo, H,, JT., Molecular, virology, clinicians., Clin, Liver, Dis, 2007;11:685-706., 8., C,, Mason, WS., biology., Microbiol, Mol, Biol, Rev, 2000;64:51-, 68., 9., Schultz, U,, Grgacic, E,, Duck, virus:, an, invaluable, model, system, HBV, infection., Adv, Virus, Res, 2004;63:1-70., 10., Schulze, A,, Gripon, P,, infection, initiates, with, a, large, surface, protein-dependent, binding, to, heparan, sulfate, proteoglycans., Hepatology, 2007;46:1759-1768., 11., Mills, K,, Weiss, TS,, Hepatocyte, polarization, is, essential, the, productive, entry, virus., 2012;55:373-383., 12., S,, Dandri, M,, Petersen, J., The, replication, cycle, Hepatol, 2010;52:282-4., 13., insights, into, delta, Future, 2008;3:253-264., 14., Rabe, B,, Kann, Lipid-mediated, introduction, capsids, nonsusceptible, cells, allows, highly, efficient, facilitates, study, early, events., 2006;80:5465-73., 15., Schmitz, B., Intracellular, transport, 2007;13:39-47., 16., Sodeik, Vlachou, Gerlich, WH,, Helenius, A., Phosphorylation-dependent, core, particles, nuclear, pore, complex., Cell, 1999;145:45-55., 17., Köck, Baumert, TF,, Delaney, WE, 4th,, Blum, HE,, von, Weizsäcker, F., Inhibitory, effect, adefovir, lamivudine, on, initiation, primary, tupaia, hepatocytes., 2003;, 38:, 1410-1418., 18., Newbold, JE,, Xin, Tencza, Sherman, G,, Dean, Bowden, Locarnini, covalently, closed, duplex, form, hepadnavirus, genome, exists, situ, as, heterogeneous, population, viral, minichromosomes., Virology, 1995;69:3350-3357., 19., Summers, Residual, integrated, DNA, after, clearance, by, nucleoside, analog, therapy., Proc, Natl, Acad, Sci, USA, 2004;101:638-40., 20., Zoulim, insight, persistence, from, intrahepatic, cccDNA., 2005;42:302-8., 21., Bock, CT,, Schwinn, et, al., Structural, organization, minichromosome., 2001;307:183-96., 22., Schadler, Hildt, E., life, cycle:, Entry, morphogenesis., Viruses, 2009;1:185-, 209., 23., virology., In, Mauss, Berg, T,, Rockstroh, Sarrazin, Wedemeyer, H, (eds)., A, Clinical, Textbook., 3rd, ed., Germany:, Flying, Hepatit, Virüsünün, Moleküler, Virolojisi" /> <title>Hepatit B'den D'ye Hep Güncel</title> <link href="style/fonts.css" type="text/css" rel="stylesheet" /> <link href="style/style.css" type="text/css" rel="stylesheet" /> <script> CURRENT_PAGE = "27"; </script> <script type="text/javascript" src="javascript/init.js"></script> <script type="text/javascript" src="javascript/properties.js"></script> <script type="text/javascript" src="javascript/seo.js"></script> <!--[if IE]> <style type="text/css"> .areaLink{ filter:progid:DXImageTransform.Microsoft.Alpha(opacity=0);} .areaLink:hover { filter:progid:DXImageTransform.Microsoft.Alpha(opacity=50);} </style> <![endif]--></head> <body> <div id="bodyBg" class="bodyBg"></div> <div id="navigation" class="navigation"> <a id="LeftToolText" class="leftTool" href="page26.html" title="26"><img src="./style/sliderleft.png" style="width: 32px; height: 69px; padding: 10px; float: left;" alt=""></a> <a id="RightToolText" class="rightTool" href="page28.html" title="28"><img src="./style/sliderright.png" style="width: 32px; height: 69px; padding: 10px; float: left;" alt=""></a> </div> <div id="Book" class="divCenter" style="width : 453px;"> <h1>Hepatit B'den D'ye Hep Güncel - page 27</h1> <div id="Page" class="divPage" style="height :666px; background-color:#FFFFFF;"> <img alt="" src="../common/page-substrates/page0027.png" style="width: 100%; height: 100%;"> <div class="div_items" style="top : 624px; left : 416px; width : 10px; height : 14px; z-index : 0;"> <span class="font1 fontPosition" style="opacity:1;">15</span> </div> <div class="div_items" style="top : 56px; left : 84px; width : 108px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Gastroenterol 2007;13:14-21.</span> </div> <div class="div_items" style="top : 67px; left : 62px; width : 7px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">3.</span> </div> <div class="div_items" style="top : 67px; left : 84px; width : 310px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Glebe D, Urban S. Viral and cellular determinants involved in hepadnaviral entry.</span> </div> <div class="div_items" style="top : 78px; left : 84px; width : 145px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">World J Gastroenterol 2007;13:22-38.</span> </div> <div class="div_items" style="top : 89px; left : 62px; width : 7px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">4.</span> </div> <div class="div_items" style="top : 89px; left : 84px; width : 267px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Ganem D, Prince AM. Hepatitis B infection: natural history and clinical</span> </div> <div class="div_items" style="top : 100px; left : 84px; width : 269px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">consequences. New England Journal of Medicine 2004;350:1118-1129.</span> </div> <div class="div_items" style="top : 111px; left : 62px; width : 7px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">5.</span> </div> <div class="div_items" style="top : 111px; left : 84px; width : 319px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Beck J, Nassal M. Hepatitis B virus replication. World J Gastroenterol 2007;13(1):48-</span> </div> <div class="div_items" style="top : 122px; left : 84px; width : 12px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">64.</span> </div> <div class="div_items" style="top : 133px; left : 62px; width : 7px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">6.</span> </div> <div class="div_items" style="top : 133px; left : 84px; width : 299px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Wang GH, Seeger C. Novel mechanism for reverse transcription in hepatitis B</span> </div> <div class="div_items" style="top : 144px; left : 84px; width : 134px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">viruses. J Virol 1993;67:6507-6512.</span> </div> <div class="div_items" style="top : 155px; left : 62px; width : 6px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">7.</span> </div> <div class="div_items" style="top : 155px; left : 84px; width : 315px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Block TM, Guo H, Guo JT. Molecular virology of hepatitis B virus for clinicians. Clin</span> </div> <div class="div_items" style="top : 166px; left : 84px; width : 101px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Liver Dis 2007;11:685-706.</span> </div> <div class="div_items" style="top : 177px; left : 62px; width : 7px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">8.</span> </div> <div class="div_items" style="top : 177px; left : 84px; width : 319px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Seeger C, Mason WS. Hepatitis B virus biology. Microbiol Mol Biol Rev 2000;64:51-</span> </div> <div class="div_items" style="top : 188px; left : 84px; width : 12px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">68.</span> </div> <div class="div_items" style="top : 199px; left : 62px; width : 7px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">9.</span> </div> <div class="div_items" style="top : 199px; left : 84px; width : 317px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Schultz U, Grgacic E, Nassal M. Duck hepatitis B virus: an invaluable model system</span> </div> <div class="div_items" style="top : 210px; left : 84px; width : 179px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">for HBV infection. Adv Virus Res 2004;63:1-70.</span> </div> <div class="div_items" style="top : 221px; left : 62px; width : 10px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">10.</span> </div> <div class="div_items" style="top : 221px; left : 84px; width : 293px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Schulze A, Gripon P, Urban S. Hepatitis B virus infection initiates with a large</span> </div> <div class="div_items" style="top : 232px; left : 84px; width : 315px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">surface protein-dependent binding to heparan sulfate proteoglycans. Hepatology</span> </div> <div class="div_items" style="top : 243px; left : 84px; width : 75px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">2007;46:1759-1768.</span> </div> <div class="div_items" style="top : 254px; left : 62px; width : 8px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">11.</span> </div> <div class="div_items" style="top : 254px; left : 84px; width : 313px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Schulze A, Mills K, Weiss TS, Urban S. Hepatocyte polarization is essential for the</span> </div> <div class="div_items" style="top : 265px; left : 84px; width : 270px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">productive entry of the hepatitis B virus. Hepatology 2012;55:373-383.</span> </div> <div class="div_items" style="top : 276px; left : 62px; width : 10px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">12.</span> </div> <div class="div_items" style="top : 276px; left : 84px; width : 319px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Urban S, Schulze A, Dandri M, Petersen J. The replication cycle of hepatitis B virus.</span> </div> <div class="div_items" style="top : 287px; left : 84px; width : 98px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">J Hepatol 2010;52:282-4.</span> </div> <div class="div_items" style="top : 298px; left : 62px; width : 10px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">13.</span> </div> <div class="div_items" style="top : 298px; left : 84px; width : 310px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Urban S. New insights into hepatitis B and hepatitis delta virus entry. Future Virol</span> </div> <div class="div_items" style="top : 309px; left : 84px; width : 66px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">2008;3:253-264.</span> </div> <div class="div_items" style="top : 320px; left : 62px; width : 10px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">14.</span> </div> <div class="div_items" style="top : 320px; left : 84px; width : 314px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Rabe B, Glebe D, Kann M. Lipid-mediated introduction of hepatitis B virus capsids</span> </div> <div class="div_items" style="top : 331px; left : 84px; width : 317px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">into nonsusceptible cells allows highly efficient replication and facilitates the study</span> </div> <div class="div_items" style="top : 342px; left : 84px; width : 194px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">of early infection events. J Virol 2006;80:5465-73.</span> </div> <div class="div_items" style="top : 353px; left : 62px; width : 10px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">15.</span> </div> <div class="div_items" style="top : 353px; left : 84px; width : 297px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Kann M, Schmitz A, Rabe B. Intracellular transport of hepatitis B virus. World J</span> </div> <div class="div_items" style="top : 364px; left : 84px; width : 111px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Gastroenterol 2007;13:39-47.</span> </div> <div class="div_items" style="top : 375px; left : 62px; width : 10px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">16.</span> </div> <div class="div_items" style="top : 375px; left : 84px; width : 320px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Kann M, Sodeik B, Vlachou A, Gerlich WH, Helenius A. Phosphorylation-dependent</span> </div> <div class="div_items" style="top : 386px; left : 84px; width : 312px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">binding of hepatitis B virus core particles to the nuclear pore complex. J Cell Biol</span> </div> <div class="div_items" style="top : 397px; left : 84px; width : 61px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">1999;145:45-55.</span> </div> <div class="div_items" style="top : 408px; left : 62px; width : 8px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">17.</span> </div> <div class="div_items" style="top : 408px; left : 84px; width : 316px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Köck J, Baumert TF, Delaney WE 4th, Blum HE, von Weizsäcker F. Inhibitory effect</span> </div> <div class="div_items" style="top : 419px; left : 84px; width : 313px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">of adefovir and lamivudine on the initiation of hepatitis B virus infection in primary</span> </div> <div class="div_items" style="top : 430px; left : 84px; width : 202px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">tupaia hepatocytes. Hepatology 2003; 38: 1410-1418.</span> </div> <div class="div_items" style="top : 441px; left : 62px; width : 10px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">18.</span> </div> <div class="div_items" style="top : 441px; left : 84px; width : 286px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Newbold JE, Xin H, Tencza M, Sherman G, Dean J, Bowden S, Locarnini S.</span> </div> <div class="div_items" style="top : 452px; left : 84px; width : 297px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">The covalently closed duplex form of the hepadnavirus genome exists in situ</span> </div> <div class="div_items" style="top : 463px; left : 84px; width : 300px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">as a heterogeneous population of viral minichromosomes. Journal of Virology</span> </div> <div class="div_items" style="top : 474px; left : 84px; width : 77px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">1995;69:3350-3357.</span> </div> <div class="div_items" style="top : 485px; left : 62px; width : 10px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">19.</span> </div> <div class="div_items" style="top : 485px; left : 84px; width : 282px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Summers J, Mason WS. Residual integrated viral DNA after hepadnavirus</span> </div> <div class="div_items" style="top : 496px; left : 84px; width : 320px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">clearance by nucleoside analog therapy. Proc Natl Acad Sci USA 2004;101:638-40.</span> </div> <div class="div_items" style="top : 507px; left : 62px; width : 13px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">20.</span> </div> <div class="div_items" style="top : 507px; left : 84px; width : 274px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Zoulim F. New insight on hepatitis B virus persistence from the study of</span> </div> <div class="div_items" style="top : 518px; left : 84px; width : 202px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">intrahepatic viral cccDNA. J Hepatol 2005;42:302-8.</span> </div> <div class="div_items" style="top : 529px; left : 62px; width : 10px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">21.</span> </div> <div class="div_items" style="top : 529px; left : 84px; width : 303px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Bock CT, Schwinn S, Locarnini S, et al. Structural organization of the hepatitis B</span> </div> <div class="div_items" style="top : 540px; left : 84px; width : 197px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">virus minichromosome. J Mol Biol 2001;307:183-96.</span> </div> <div class="div_items" style="top : 551px; left : 62px; width : 12px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">22.</span> </div> <div class="div_items" style="top : 551px; left : 84px; width : 313px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Schadler S, Hildt E. HBV life cycle: Entry and morphogenesis. Viruses 2009;1:185-</span> </div> <div class="div_items" style="top : 562px; left : 84px; width : 18px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">209.</span> </div> <div class="div_items" style="top : 573px; left : 62px; width : 12px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">23.</span> </div> <div class="div_items" style="top : 573px; left : 84px; width : 307px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Dandri M, Petersen J. HBV virology. In Mauss S, Berg T, Rockstroh J, Sarrazin C,</span> </div> <div class="div_items" style="top : 584px; left : 84px; width : 300px; height : 13px; z-index : 0;"> <span class="font4 fontPosition" style="opacity:1;">Wedemeyer H (eds). Hepatology A Clinical Textbook. 3rd ed. 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